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Nipples can be sensitive to touch, and nipple stimulation can incite sexual arousal.Komisaruk's study was the first to map the female genitals onto the sensory portion of the brain; it indicates that sensation from the nipples travels to the same part of the brain as sensations from the vagina, clitoris and cervix, and that these reported orgasms are genital orgasms caused by nipple stimulation, and may be directly linked to the genital sensory cortex ("the genital area of the brain").Nipple pain can also be caused by excessive friction of clothing against the nipple that causes a fissure.
The rest of the drainage leaves the nipple and breast through infroclavicular, pectoral, or parasternal nodes.
The physiological purpose of nipples is to deliver milk to the infant, produced in the female mammary glands during lactation.
Marsupials and eutherian mammals typically have an even number of nipples arranged bilaterally, from as few as two to as many as 19.
Oxytocin release from the nipple stimulation of the infant causes the uterus to contract even after childbirth.
The strong uterine contractions that are caused by the stimulation of the mother's nipples help the uterus contract to clamp down the uterine arteries.
After the birth of the infant, the milk supply increases based upon the continuous and increasing stimulation of the nipple by the infant.